A statistical approach for tracking clonal dynamics in cancer using longitudinal next-generation sequencing data

A statistical approach for tracking clonal dynamics in cancer using longitudinal next-generation sequencing data

Motivation: The tumor is composed of different cancer cell population (clones), which continues to adapt to their local microenvironment. the standard method for deconvolution clonal mutation group seeks to identify and estimate the prevalence of each group in the tumor, while taking into account the purity and copy number profile. This method has been applied to a cross-sectional and longitudinal data after removing information about the time of sample collection.

Two key question is how we can combine the information in our analyzes and there are benefits in doing so?
Results: We developed clonal deconvolution method, which combines explicit temporal distance longitudinal tumor samples. By combining the Dirichlet Process Mixture Model Gaussian Process priors and used as an input sequence is rarely collected several samples, our method can reconstruct the temporal profile mutation abundance of each cluster is supported by data as a continuous function of time.

We refer to our method on the whole genome, whole exome and sequencing data targeted from patients with chronic lymphocytic leukemia, the data biopsy fluid of patients with melanoma and synthetic data and we found that combining information about a collection of networks improve the performance of the model, as long as the data volume and complexity is available for the free estimate model parameters. Thus, our approach is very useful when collecting a relatively long sequences of tumor samples feasible, such as in liquid cancers (eg, leukemia) and liquid biopsy.


Bactrian camel population size smaller than the dromedary, and they are distributed in the cold and mountain regions and also at risk of extinction in some countries such as Iran. To identify and investigate genome-wide variation, whole-genome sequencing of two Bactrian camels Iran do with the scope 37.4- and 42.6-fold for the first time. Along with Iran Bactrian camel, sequencing data from two domestic and two Mongolian wild Bactrian camel is stored in the NCBI reanalyzed.

 A statistical approach for tracking clonal dynamics in cancer using longitudinal next-generation sequencing data
A statistical approach for tracking clonal dynamics in cancer using longitudinal next-generation sequencing data

scPADGRN: An asphalt ADMM approach to reconstruct gene regulatory networks dynamically using RNA sequencing data-single cell

development and cell differentiation disease both involve dynamic changes; Therefore, reconstruction of dynamic gene regulatory network (DGRNs) is an important issue but it is difficult in biological systems. With recent advances in single-cell technical RNA sequencing (scRNA-seq), a large volume of data scRNA-seq is being obtained for the various processes. However, current methods of concluding DGRNs of the bulk sample may not be suitable for data-seq scRNA.

In this work, we present scPADGRN, inference DGRN new method using “time-series” scRNA-seq data. scPADGRN combining the method of alternating directions asphalt multiplier by grouping cells for reconstruction DGRN. It shows the advantages in accuracy, robustness and fast convergence. In addition, so-called quantitative index Differentiation Gene Interactions Enrichment (DGIE) served to measure the interaction enrichment of genes related to differentiation.

From the score DGIE of the relevant subnetwork, we conclude that the function of embryonic stem (ES) cells are most active initially and may gradually fade over time. Communication power of genes contribute to note that facilitate the differentiation of cells increased from ES cells differentiated into severe cells.

1L SequaGel XR
NAT1162 1L
EUR 138.00
1L SequaGel UreaGel Concentrate
NAT1134 1L
EUR 134.00
1L SequaGel UreaGel-6
NAT1146 1L
EUR 126.00
1L SequaGel UreaGel-8
NAT1150 1L
EUR 126.00
1L SequaGel UreaGel Diluent
NAT1154 1L
EUR 86.00
sequencing system 20x50 cm
ESEQ1200-SYS ea
EUR 1535.00
REAGENT BOTTLE, 1L, PP
1500P-1L 10/pk
EUR 100.00
Description: Reusable Plastics; Resusable Bottles
UreaGel 29:1 System 1L Kit
NAT1128 EACH
EUR 143.00
BEAKER,1L,PLASTIC,LOW FORM,PP,6/6
1000P-1L 6/pk
EUR 63.00
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BEAKER,1L,PLASTIC,LOW FORM,PFA,1/6
1003P-1L 1/pk
EUR 653.00
Description: Reusable Plastics; Resuable Beakers
BEAKER,1L,WITH HANDLE AND SPOUT,PP,12/12
1015P-1L 12/pk
EUR 116.00
Description: Reusable Plastics; Resuable Beakers
SequaGel MD SSCP Kit
NAT1170 1KIT
EUR 211.00
SequaGel MD Heteroduplex Kit
NAT1172 EACH
EUR 221.00
CYLINDER,GRAD,1L,PLASTIC,SINGLE METRIC SCALE,PP,TC W/FUNNEL,1/6
3022P-1L 1/pk
EUR 161.00
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VOL FLASK,1L,PLASTIC,CLASS A,PMP,24/29 TAPERED PP STOPPER,1/3
5640P-1L 1/pk
EUR 133.00
Description: Reusable Plastics; Reusable Volumetric Flasks
VOL FLASK,1L,PLASTIC,CLASS B,PP,24/29 TAPERED PP STOPPER,1/3
5641P-1L 1/pk
EUR 121.00
Description: Reusable Plastics; Reusable Volumetric Flasks
100ML SequaGel Buffer
NAT1140 100ML
EUR 67.00
450ML SequaGel XR
NAT1160 450ML
EUR 105.00
PinPoint-HR System for Platform Cell Line Generation & Retargeting (includes PIN400A-1, PIN200A-1, PIN510A-1, & PIN600A-1)
PIN400A-KIT 1 Kit
EUR 2798.00
  • Category: PinPoint Integrase Tools
PinPoint-FC System for Platform Cell Line Generation & Retargeting (includes PIN300A-1, FC200PA-1, PIN200A-1, PIN510A-1, & PIN600A-1)
PIN300A-KIT 1 Kit
EUR 2798.00
  • Category: PinPoint Integrase Tools
Chymotrypsin for Sequencing grade
C4001-010 4x25ug
EUR 313.00
Chymotrypsin for Sequencing grade
C4001-100 100ug
EUR 286.00
sequencing unit 33x45 cm
ESEQ1100-SYS ea
EUR 1535.00
Trypin for Mass & Sequencing
T9600-025 25ug
EUR 145.00
Trypin for Mass & Sequencing
T9600-100 100ug
EUR 219.00
Trypin for Mass & Sequencing
T9600-112 12x100ug
EUR 1657.00
Trypin for Mass & Sequencing
T9600-400 4x100ug
EUR 651.00
450ML SequaGel UreaGel Concentrate
NAT1132 450ML
EUR 105.00
200ML SequaGel UreaGel Buffer
NAT1142 200ML
EUR 70.00
450ML SequaGel UreaGel-6
NAT1144 450ML
EUR 96.00
450ML SequaGel UreaGel-8
NAT1148 450ML
EUR 96.00
450ML SequaGel UreaGel Diluent
NAT1152 450ML
EUR 75.00
90ML SequaGel Complete Buffer
NAT1156 90ML
EUR 66.00
100ML SequaGel XR Concentrate
NAT1164 100ML
EUR 107.00
450ML SequaGel XR Concentrate
NAT1166 450ML
EUR 301.00
PinPoint-HR System for Platform Cell Line Generation & Retargeting of AAVS1 Safe Harbor Locus (includes PIN410A-1, GE601A-1, PIN200A-1, PIN510A-1, & PIN600A-1)
PIN410A-KIT 1 Kit
EUR 4335.00
  • Category: PinPoint Integrase Tools
PinPoint-HR System for Platform Cell Line Generation & Retargeting of AAVS1 Safe Harbor Locus (includes PIN410A-1, CAS601A-1, PIN200A-1, PIN510A-1, & PIN600A-1)
PIN412A-KIT 1 Kit
EUR 4335.00
  • Category: PinPoint Integrase Tools
1L HarrisHematoxylin
NAT1338 1L
EUR 123.00
1L Autofluor
NAT1446 1L
EUR 216.00
200ML SequaGel UreaGel Complete Buffer
NAT1158 200ML
EUR 71.00
200ML SequaGel MD Monomer Solution
NAT1168 200ML
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PCR Clean Up for DNA Sequencing
BT5100 100preps
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SLINGSHOT-1L Antibody
48407-100ul 100ul
EUR 333.00
SLINGSHOT-1L Antibody
48407-50ul 50ul
EUR 239.00
PLASTIC CLAMP, 1L
480152 1/pk
EUR 73.00
Description: Lab Equipment; Constant Temperature Equipment
SLINGSHOT-1L Antibody
abx016133-100ug 100 ug
EUR 411.00
  • Shipped within 5-10 working days.
SLINGSHOT-1L Antibody
abx224128-100ug 100 ug
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  • Product category: Labware/Lab Accessories/Brushes
Dermcidin-1L (human)
H-7316.0500 0.5mg
EUR 177.00
Description: Sum Formula: C210H359N57O71; CAS# [478898-18-9] net
Dermcidin-1L (human)
H-7316.1000 1.0mg
EUR 294.00
Description: Sum Formula: C210H359N57O71; CAS# [478898-18-9] net
1L-chiro-Inositol
GC7626-100MG 100 mg
EUR 102.00
1L-chiro-Inositol
GC7626-1G 1 g
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NAT1084 1L
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NAT1108 1L
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NAT1112 1L
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1L AcrylaGel 30%
NAT1118 1L
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NAT1200 1L
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NAT1234 1L
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NAT1264 1L
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1L Opticlear Sample Kit I
NAT1494 1L
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1L Opticlear Sample Kit II
NAT1496 1L
EUR 179.00
1.2ML SequaGel MD SSCP Stop Solution
NAT1174 1.2ML
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Frit Kit
FRIT-KIT 1each
EUR 124.00
Description: Kit to create frits in capillaries. Includes formamide, Kasil-1, Kasil-1624 and a cleaving tool.
Column Packing Kit
PACK-KIT 1pack
EUR 1035.00
Description: Column packing kit for pressure cells. Includes: HPREG regulator, TBNG10 tubing, CAP-75 capillary, and STRB5X2 stir bar.
PCR Mycoplasma Detection Kit
M034-Kit Kit
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Human Metallothionein- 1L, MT1L ELISA KIT
ELI-36664h 96 Tests
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Human Metallothionein 1L(MT1L)ELISA Kit
QY-E02761 96T
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CELL EXPANSION BAG, 1L
91-200-85 1/pk
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SLINGSHOT-1L Conjugated Antibody
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  • Shelf time: 2 years
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NAT1268 1L
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1L EDTA 0.5M Solution
NAT1282 1L
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Cas9 Protein and T7 gRNA SmartNuclease Synthesis Kit
CAS400A-KIT 1 kit (10 rxn)
EUR 1110.00
  • Category: Cas9
CMV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit
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EUR 1132.00
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MSCV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit
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MSCV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit
CASLV125PA-KIT 1 Kit
EUR 1132.00
  • Category: Cas9
Multiplex gRNA Kit + EF1-T7-hspCas9-H1-gRNA linearized SmartNuclease vector
CAS700A-KIT 10 rxn
EUR 1132.00
  • Category: Cas9
Multiplex gRNA Kit + CAG-T7-hspCas9-H1-gRNA linearized SmartNuclease vector
CAS720A-KIT 10 rxn
EUR 1132.00
  • Category: Cas9
Multiplex gRNA Kit + CMV-T7-hspCas9-H1-gRNA linearized SmartNuclease vector
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EUR 1132.00
  • Category: Cas9
T7 gRNA SmartNuclease Synthesis Kit (includes CAS510A-1 & T7 IVT synthesis reagents)
CAS510A-KIT 1 Kit
EUR 805.00
  • Category: Cas9
Cas9 Nickase: CMV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit
CASLV200PA-KIT 1 Kit
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  • Category: Cas9
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  • Category: Cas9
Cas9 Nickase: MSCV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit
CASLV220PA-KIT 1 Kit
EUR 1132.00
  • Category: Cas9
Cas9 Nickase: MSCV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit
CASLV225PA-KIT 1 Kit
EUR 1132.00
  • Category: Cas9
Multiplex gRNA Kit + Cas9 Nickase: EF1-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector
CAS750A-KIT 10 rxn
EUR 1132.00
  • Category: Cas9
Multiplex gRNA Kit + Cas9 Nickase: CAG-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector
CAS770A-KIT 10 rxn
EUR 1132.00
  • Category: Cas9
Multiplex gRNA Kit + Cas9 Nickase: CMV-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector
CAS790A-KIT 10 rxn
EUR 1132.00
  • Category: Cas9
Cas9 SmartNuclease Extra Ligation Kit [includes 5x ligation buffer (10 ul) and Fast ligase (2.5ul)]
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EUR 153.00
  • Category: Cas9
PinPoint-FC 293T Platform Kit for Targeted Gene Insertion (includes PIN320A-1, PIN200A-1, PIN510A-1 & PIN600A-1)
PIN320A-KIT 1 Kit
EUR 4941.00
  • Category: PinPoint Integrase Tools
PinPoint-FC Murine iPSC Platform Kit for Targeted Gene Insertion (includes PIN340iPS-1, PIN200A-1, PIN510A-1 & PIN600A-1)
PIN340iPS-KIT 1 Kit
EUR 4941.00
  • Category: PinPoint Integrase Tools
Bovine Protein phosphatase 1L, PPM1L ELISA KIT
ELI-36194b 96 Tests
EUR 928.00
Human Protein phosphatase 1L, PPM1L ELISA KIT
ELI-45425h 96 Tests
EUR 824.00
Mouse Protein phosphatase 1L, Ppm1l ELISA KIT
ELI-36546m 96 Tests
EUR 865.00
ELISA kit for Human Metallothionein-1L (MT1L)
KTE61511-48T 48T
EUR 332.00
  • MT1L (Metallothionein 1L (Gene/Pseudogene)) is a Protein Coding gene. Metallothioneins have a high content of cysteine residues that bind various heavy metals
  • these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
Description: Quantitative sandwich ELISA for measuring Human Metallothionein-1L (MT1L) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Human Metallothionein-1L (MT1L)
KTE61511-5platesof96wells 5 plates of 96 wells
EUR 2115.00
  • MT1L (Metallothionein 1L (Gene/Pseudogene)) is a Protein Coding gene. Metallothioneins have a high content of cysteine residues that bind various heavy metals
  • these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
Description: Quantitative sandwich ELISA for measuring Human Metallothionein-1L (MT1L) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Human Metallothionein-1L (MT1L)
KTE61511-96T 96T
EUR 539.00
  • MT1L (Metallothionein 1L (Gene/Pseudogene)) is a Protein Coding gene. Metallothioneins have a high content of cysteine residues that bind various heavy metals
  • these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
Description: Quantitative sandwich ELISA for measuring Human Metallothionein-1L (MT1L) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
COLLECTION CONTAINER 1L, EVA FILM
91-200-01 1/pk
EUR 80.00
Description: Flexible Containers; Bioprocess Bags and Parts
COLLECTION CONTAINER 1L, EVA FILM
91-200-42 1/pk
EUR 73.00
Description: Flexible Containers; Bioprocess Bags and Parts
CLAMP FOR 1L ERLENMYER FLASK
480115 1/pk
EUR 63.00
Description: Lab Equipment; Shakers & Mixers
ICE PAN, MINI, 1L GREEN
432115 1/pk
EUR 93.00
Description: BioCision; BioCision TruCool
ICE PAN, MINI, 1L BLUE
432116 1/pk
EUR 93.00
Description: BioCision; BioCision TruCool
ICE PAN, MINI, 1L RED
432117 1/pk
EUR 93.00
Description: BioCision; BioCision TruCool
ICE PAN, MINI, 1L ORANGE
432118 1/pk
EUR 93.00
Description: BioCision; BioCision TruCool
ICE PAN, MINI, 1L PINK
432120 1/pk
EUR 93.00
Description: BioCision; BioCision TruCool
ICE PAN, MINI, 1L PURPLE
432121 1/pk
EUR 93.00
Description: BioCision; BioCision TruCool
Recombinant human Protein phosphatase 1L
P1206 100ug Ask for price
  • Uniprot ID: Q5SGD2
  • Reconstitution: Metal affinity chromatography on Fn Super Capacity Column (Nickel)
Description: Recombinant protein for human Protein phosphatase 1L
1L UreaGel 29:1 Concentrate
NAT1126 1L
EUR 153.00
1L AccuGel 19:1 (30%)
NAT1178 1L
EUR 138.00
1L AccuGel 19:1 (40%)
NAT1182 1L
EUR 140.00
1L AccuGel 29:1 (30%)
NAT1186 1L
EUR 138.00
1L AccuGel 29:1 (40%)
NAT1190 1L
EUR 140.00
1L Sodium Chloride 0.009 Solution
NAT1284 1L
EUR 117.00
1L Sodium Chloride 1M Solution
NAT1286 1L
EUR 117.00
1L Potassium Chloride 1M Solution
NAT1288 1L
EUR 117.00
ProtoBlock System
NAT1004 1KIT
EUR 102.00
AAVS1 Safe Harbor Targeting Vector 2.0 - All-Purpose Donor (AAVS1-SA-puro-MCS), Complete Kit with CAS601A-1 (Cas9 SmartNuclease AAVS1-gRNA Targeting Vector) and GE640PR-1 (Junction PCR Primer Mix to confirm AAVS1 integration site)
GE620A-KIT 1 kit
EUR 2132.00
  • Category: Gene Editing
AAVS1 Safe Harbor Targeting Vector 2.0 - GOI Knock-in Donor (AAVS1-SA-puro-EF1-MCS), Complete Kit with CAS601A-1 (Cas9 SmartNuclease AAVS1-gRNA Targeting Vector) and GE640PR-1 (Junction PCR Primer Mix to confirm AAVS1 integration site)
GE622A-KIT 1 kit
EUR 2132.00
  • Category: Gene Editing
AAVS1 Safe Harbor Targeting Vector 2.0 - Reporter Knock-in Donor (AAVS1-SA-puro-MCS-GFP), Complete Kit with CAS601A-1 (Cas9 SmartNuclease AAVS1-gRNA Targeting Vector) and GE640PR-1 (Junction PCR Primer Mix to confirm AAVS1 integration site)
GE624A-KIT 1 kit
EUR 2132.00
  • Category: Gene Editing
Human Retinoic Acid Early Transcript 1L ELISA kit
E01R0358-192T 192 tests
EUR 1270.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Human Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Human Retinoic Acid Early Transcript 1L ELISA kit
E01R0358-48 1 plate of 48 wells
EUR 520.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Human Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Human Retinoic Acid Early Transcript 1L ELISA kit
E01R0358-96 1 plate of 96 wells
EUR 685.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Human Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rat Retinoic Acid Early Transcript 1L ELISA kit
E02R0358-192T 192 tests
EUR 1270.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Rat Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rat Retinoic Acid Early Transcript 1L ELISA kit
E02R0358-48 1 plate of 48 wells
EUR 520.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Rat Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rat Retinoic Acid Early Transcript 1L ELISA kit
E02R0358-96 1 plate of 96 wells
EUR 685.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Rat Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Pig Retinoic Acid Early Transcript 1L ELISA kit
E07R0358-192T 192 tests
EUR 1270.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Porcine Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Pig Retinoic Acid Early Transcript 1L ELISA kit
E07R0358-48 1 plate of 48 wells
EUR 520.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Porcine Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Pig Retinoic Acid Early Transcript 1L ELISA kit
E07R0358-96 1 plate of 96 wells
EUR 685.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Porcine Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rabbit Retinoic Acid Early Transcript 1L ELISA kit
E04R0358-192T 192 tests
EUR 1270.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Rabbit Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rabbit Retinoic Acid Early Transcript 1L ELISA kit
E04R0358-48 1 plate of 48 wells
EUR 520.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Rabbit Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rabbit Retinoic Acid Early Transcript 1L ELISA kit
E04R0358-96 1 plate of 96 wells
EUR 685.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Rabbit Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Goat Retinoic Acid Early Transcript 1L ELISA kit
E06R0358-192T 192 tests
EUR 1270.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Goat Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Goat Retinoic Acid Early Transcript 1L ELISA kit
E06R0358-48 1 plate of 48 wells
EUR 520.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Goat Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Goat Retinoic Acid Early Transcript 1L ELISA kit
E06R0358-96 1 plate of 96 wells
EUR 685.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Goat Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Mouse Retinoic Acid Early Transcript 1L ELISA kit
E03R0358-192T 192 tests
EUR 1270.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Mouse Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Mouse Retinoic Acid Early Transcript 1L ELISA kit
E03R0358-48 1 plate of 48 wells
EUR 520.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Mouse Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Mouse Retinoic Acid Early Transcript 1L ELISA kit
E03R0358-96 1 plate of 96 wells
EUR 685.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Mouse Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Monkey Retinoic Acid Early Transcript 1L ELISA kit
E09R0358-192T 192 tests
EUR 1270.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Monkey Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Monkey Retinoic Acid Early Transcript 1L ELISA kit
E09R0358-48 1 plate of 48 wells
EUR 520.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Monkey Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Monkey Retinoic Acid Early Transcript 1L ELISA kit
E09R0358-96 1 plate of 96 wells
EUR 685.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Monkey Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Dog Retinoic Acid Early Transcript 1L ELISA kit
E08R0358-192T 192 tests
EUR 1270.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Canine Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Dog Retinoic Acid Early Transcript 1L ELISA kit
E08R0358-48 1 plate of 48 wells
EUR 520.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Canine Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Dog Retinoic Acid Early Transcript 1L ELISA kit
E08R0358-96 1 plate of 96 wells
EUR 685.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Canine Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
BCA Protein Assay Kit
AR0146-1L 1kit
EUR 456.00
vWF Acty. Kit
ABP-ACT-KIT 12 x 8 microwells
EUR 428.00
vWF Ant. Kit
ABP-TOT-KIT 12 x 8 microwells
EUR 394.00

We also identified some of the genes responsible for the change in the score DGIE occur during cell differentiation is based on three single-cell dataset real. Our results show that single-cell analysis is based on inference network coupled with quantitative calculations can reveal key transcriptional regulators involved in cell differentiation and disease progression.

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