A statistical approach for tracking clonal dynamics in cancer using longitudinal next-generation sequencing data

A statistical approach for tracking clonal dynamics in cancer using longitudinal next-generation sequencing data

Motivation: The tumor is composed of different cancer cell population (clones), which continues to adapt to their local microenvironment. the standard method for deconvolution clonal mutation group seeks to identify and estimate the prevalence of each group in the tumor, while taking into account the purity and copy number profile. This method has been applied to a cross-sectional and longitudinal data after removing information about the time of sample collection.

Two key question is how we can combine the information in our analyzes and there are benefits in doing so?
Results: We developed clonal deconvolution method, which combines explicit temporal distance longitudinal tumor samples. By combining the Dirichlet Process Mixture Model Gaussian Process priors and used as an input sequence is rarely collected several samples, our method can reconstruct the temporal profile mutation abundance of each cluster is supported by data as a continuous function of time.

We refer to our method on the whole genome, whole exome and sequencing data targeted from patients with chronic lymphocytic leukemia, the data biopsy fluid of patients with melanoma and synthetic data and we found that combining information about a collection of networks improve the performance of the model, as long as the data volume and complexity is available for the free estimate model parameters. Thus, our approach is very useful when collecting a relatively long sequences of tumor samples feasible, such as in liquid cancers (eg, leukemia) and liquid biopsy.


Bactrian camel population size smaller than the dromedary, and they are distributed in the cold and mountain regions and also at risk of extinction in some countries such as Iran. To identify and investigate genome-wide variation, whole-genome sequencing of two Bactrian camels Iran do with the scope 37.4- and 42.6-fold for the first time. Along with Iran Bactrian camel, sequencing data from two domestic and two Mongolian wild Bactrian camel is stored in the NCBI reanalyzed.

 A statistical approach for tracking clonal dynamics in cancer using longitudinal next-generation sequencing data
A statistical approach for tracking clonal dynamics in cancer using longitudinal next-generation sequencing data

scPADGRN: An asphalt ADMM approach to reconstruct gene regulatory networks dynamically using RNA sequencing data-single cell

development and cell differentiation disease both involve dynamic changes; Therefore, reconstruction of dynamic gene regulatory network (DGRNs) is an important issue but it is difficult in biological systems. With recent advances in single-cell technical RNA sequencing (scRNA-seq), a large volume of data scRNA-seq is being obtained for the various processes. However, current methods of concluding DGRNs of the bulk sample may not be suitable for data-seq scRNA.

In this work, we present scPADGRN, inference DGRN new method using “time-series” scRNA-seq data. scPADGRN combining the method of alternating directions asphalt multiplier by grouping cells for reconstruction DGRN. It shows the advantages in accuracy, robustness and fast convergence. In addition, so-called quantitative index Differentiation Gene Interactions Enrichment (DGIE) served to measure the interaction enrichment of genes related to differentiation.

From the score DGIE of the relevant subnetwork, we conclude that the function of embryonic stem (ES) cells are most active initially and may gradually fade over time. Communication power of genes contribute to note that facilitate the differentiation of cells increased from ES cells differentiated into severe cells.

1L SequaGel UreaGel-6

NAT1146 1L
EUR 126

1L SequaGel UreaGel-8

NAT1150 1L
EUR 126

1L SequaGel UreaGel Diluent

NAT1154 1L
EUR 86

sequencing system 20x50 cm

ESEQ1200-SYS ea
EUR 1535

REAGENT BOTTLE, 1L, PP

1500P-1L 10/pk
EUR 100
Description: Reusable Plastics; Resusable Bottles

UreaGel 29:1 System 1L Kit

NAT1128 EACH
EUR 143

BEAKER,1L,PLASTIC,LOW FORM,PP,6/6

1000P-1L 6/pk
EUR 63
Description: Reusable Plastics; Resuable Beakers

BEAKER,1L,PLASTIC,LOW FORM,PFA,1/6

1003P-1L 1/pk
EUR 653
Description: Reusable Plastics; Resuable Beakers

BEAKER,1L,WITH HANDLE AND SPOUT,PP,12/12

1015P-1L 12/pk
EUR 116
Description: Reusable Plastics; Resuable Beakers

SequaGel MD SSCP Kit

NAT1170 1KIT
EUR 211

SequaGel MD Heteroduplex Kit

NAT1172 EACH
EUR 221

CYLINDER,GRAD,1L,PLASTIC,SINGLE METRIC SCALE,PP,TC W/FUNNEL,1/6

3022P-1L 1/pk
EUR 161
Description: Reusable Plastics; Reusable Cylinders

100ML SequaGel Buffer

NAT1140 100ML
EUR 67

450ML SequaGel XR

NAT1160 450ML
EUR 105

VOL FLASK,1L,PLASTIC,CLASS A,PMP,24/29 TAPERED PP STOPPER,1/3

5640P-1L 1/pk
EUR 133
Description: Reusable Plastics; Reusable Volumetric Flasks

VOL FLASK,1L,PLASTIC,CLASS B,PP,24/29 TAPERED PP STOPPER,1/3

5641P-1L 1/pk
EUR 121
Description: Reusable Plastics; Reusable Volumetric Flasks

sequencing unit 33x45 cm

ESEQ1100-SYS ea
EUR 1535

Chymotrypsin for Sequencing grade

C4001-010 4x25ug
EUR 313

Chymotrypsin for Sequencing grade

C4001-100 100ug
EUR 286

Trypin for Mass & Sequencing

T9600-025 25ug
EUR 145

Trypin for Mass & Sequencing

T9600-100 100ug
EUR 219

Trypin for Mass & Sequencing

T9600-112 12x100ug
EUR 1657

Trypin for Mass & Sequencing

T9600-400 4x100ug
EUR 651

450ML SequaGel UreaGel Concentrate

NAT1132 450ML
EUR 105

200ML SequaGel UreaGel Buffer

NAT1142 200ML
EUR 70

450ML SequaGel UreaGel-6

NAT1144 450ML
EUR 96

450ML SequaGel UreaGel-8

NAT1148 450ML
EUR 96

450ML SequaGel UreaGel Diluent

NAT1152 450ML
EUR 75

90ML SequaGel Complete Buffer

NAT1156 90ML
EUR 66

100ML SequaGel XR Concentrate

NAT1164 100ML
EUR 107

450ML SequaGel XR Concentrate

NAT1166 450ML
EUR 301

PinPoint-HR System for Platform Cell Line Generation & Retargeting (includes PIN400A-1, PIN200A-1, PIN510A-1, & PIN600A-1)

PIN400A-KIT 1 Kit
EUR 2798

PinPoint-FC System for Platform Cell Line Generation & Retargeting (includes PIN300A-1, FC200PA-1, PIN200A-1, PIN510A-1, & PIN600A-1)

PIN300A-KIT 1 Kit
EUR 2798

1L HarrisHematoxylin

NAT1338 1L
EUR 123

1L Autofluor

NAT1446 1L
EUR 216

DNA Library Prep Kit for IIlumina Sequencing

K1475-12 12 Rxns
EUR 480

PinPoint-HR System for Platform Cell Line Generation & Retargeting of AAVS1 Safe Harbor Locus (includes PIN410A-1, GE601A-1, PIN200A-1, PIN510A-1, & PIN600A-1)

PIN410A-KIT 1 Kit
EUR 4335

PinPoint-HR System for Platform Cell Line Generation & Retargeting of AAVS1 Safe Harbor Locus (includes PIN410A-1, CAS601A-1, PIN200A-1, PIN510A-1, & PIN600A-1)

PIN412A-KIT 1 Kit
EUR 4335

200ML SequaGel UreaGel Complete Buffer

NAT1158 200ML
EUR 71

200ML SequaGel MD Monomer Solution

NAT1168 200ML
EUR 184

PCR Clean Up for DNA Sequencing

BT5100 100preps
EUR 95.68

PCR Clean Up for DNA Sequencing

BT5101 1000Preps, 1000prep
EUR 461.08

1L-chiro-Inositol

GC7626-1G 1 g
EUR 269

1L-chiro-Inositol

GC7626-100MG 100 mg
EUR 102

1L Tween 20

NAT1084 1L
EUR 141

1L ProtoBlue Safe

NAT1108 1L
EUR 133

1L ProtoStain Blue

NAT1112 1L
EUR 137

1L AcrylaGel 30%

NAT1118 1L
EUR 148

1L TBE 10X

NAT1196 1L
EUR 82

1L TBE 5X

NAT1200 1L
EUR 77

1L Denaturation Solution

NAT1232 1L
EUR 85

1L Neutralization Solution

NAT1234 1L
EUR 85

1L ProtoGel (30%)

NAT1260 1L
EUR 156

1L ProtoGel (40%)

NAT1264 1L
EUR 170

1L Scotts Tapwater

NAT1342 1L
EUR 75

1L Oxosol 306

NAT1382 1L
EUR 112

PLASTIC CLAMP, 1L

480152 1/pk
EUR 73
Description: Lab Equipment; Constant Temperature Equipment

Beaker Brushes, 1L

BR007-1K 1 UNIT
EUR 53.48

SLINGSHOT-1L Antibody

abx016133-100ug 100 ug
EUR 411

SLINGSHOT-1L Antibody

abx224128-100ug 100 ug
EUR 411

SLINGSHOT-1L Antibody

48407-100ul 100ul
EUR 333

SLINGSHOT-1L Antibody

48407-50ul 50ul
EUR 239

Dermcidin-1L (human)

H-7316.0500 0.5mg
EUR 177
Description: Sum Formula: C210H359N57O71; CAS# [478898-18-9] net

Dermcidin-1L (human)

H-7316.1000 1.0mg
EUR 294
Description: Sum Formula: C210H359N57O71; CAS# [478898-18-9] net

1L Opticlear Sample Kit I

NAT1494 1L
EUR 162

1L Opticlear Sample Kit II

NAT1496 1L
EUR 179

1.2ML SequaGel MD SSCP Stop Solution

NAT1174 1.2ML
EUR 71

Human Metallothionein 1L(MT1L)ELISA Kit

QY-E02761 96T
EUR 361

Human Metallothionein- 1L, MT1L ELISA KIT

ELI-36664h 96 Tests
EUR 824

Frit Kit

FRIT-KIT 1each
EUR 124
Description: Kit to create frits in capillaries. Includes formamide, Kasil-1, Kasil-1624 and a cleaving tool.

1L DEPC Treated Water

NAT1104 1L
EUR 100

1L Bis-AcrylaGel 2%

NAT1122 1L
EUR 93

1L TAE Buffer 50X

NAT1222 1L
EUR 124

1L SSC Buffer 20X

NAT1224 1L
EUR 82

1L ProtoGel Resolving Buffer

NAT1268 1L
EUR 107

1L EDTA 0.5M Solution

NAT1282 1L
EUR 153

InstantBlue 1L (Instant Blue)

ISB1L 1L bottle
EUR 165

CELL EXPANSION BAG, 1L

91-200-85 1/pk
EUR 112
Description: Flexible Containers; Bioprocess Bags and Parts

SLINGSHOT-1L Conjugated Antibody

C48407 100ul
EUR 397

Column Packing Kit

PACK-KIT 1pack
EUR 1035
Description: Column packing kit for pressure cells. Includes: HPREG regulator, TBNG10 tubing, CAP-75 capillary, and STRB5X2 stir bar.

PCR Mycoplasma Detection Kit

M034-Kit Kit
EUR 266

ELISA kit for Human Metallothionein-1L (MT1L)

KTE61511-48T 48T
EUR 332
Description: Quantitative sandwich ELISA for measuring Human Metallothionein-1L (MT1L) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Metallothionein-1L (MT1L)

KTE61511-5platesof96wells 5 plates of 96 wells
EUR 2115
Description: Quantitative sandwich ELISA for measuring Human Metallothionein-1L (MT1L) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Metallothionein-1L (MT1L)

KTE61511-96T 96T
EUR 539
Description: Quantitative sandwich ELISA for measuring Human Metallothionein-1L (MT1L) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Human Protein phosphatase 1L, PPM1L ELISA KIT

ELI-45425h 96 Tests
EUR 824

Bovine Protein phosphatase 1L, PPM1L ELISA KIT

ELI-36194b 96 Tests
EUR 928

Mouse Protein phosphatase 1L, Ppm1l ELISA KIT

ELI-36546m 96 Tests
EUR 865

Cas9 Protein and T7 gRNA SmartNuclease Synthesis Kit

CAS400A-KIT 1 kit (10 rxn)
EUR 1110

ProtoBlock System

NAT1004 1KIT
EUR 102

1L UreaGel 29:1 Concentrate

NAT1126 1L
EUR 153

1L AccuGel 19:1 (30%)

NAT1178 1L
EUR 138

1L AccuGel 19:1 (40%)

NAT1182 1L
EUR 140

1L AccuGel 29:1 (30%)

NAT1186 1L
EUR 138

1L AccuGel 29:1 (40%)

NAT1190 1L
EUR 140

1L Sodium Chloride 0.009 Solution

NAT1284 1L
EUR 117

1L Sodium Chloride 1M Solution

NAT1286 1L
EUR 117

1L Potassium Chloride 1M Solution

NAT1288 1L
EUR 117

COLLECTION CONTAINER 1L, EVA FILM

91-200-01 1/pk
EUR 80
Description: Flexible Containers; Bioprocess Bags and Parts

COLLECTION CONTAINER 1L, EVA FILM

91-200-42 1/pk
EUR 73
Description: Flexible Containers; Bioprocess Bags and Parts

ICE PAN, MINI, 1L GREEN

432115 1/pk
EUR 93
Description: BioCision; BioCision TruCool

ICE PAN, MINI, 1L BLUE

432116 1/pk
EUR 93
Description: BioCision; BioCision TruCool

ICE PAN, MINI, 1L RED

432117 1/pk
EUR 93
Description: BioCision; BioCision TruCool

ICE PAN, MINI, 1L ORANGE

432118 1/pk
EUR 93
Description: BioCision; BioCision TruCool

ICE PAN, MINI, 1L PINK

432120 1/pk
EUR 93
Description: BioCision; BioCision TruCool

ICE PAN, MINI, 1L PURPLE

432121 1/pk
EUR 93
Description: BioCision; BioCision TruCool

CLAMP FOR 1L ERLENMYER FLASK

480115 1/pk
EUR 63
Description: Lab Equipment; Shakers & Mixers

Recombinant human Protein phosphatase 1L

P1206 100ug Ask for price
Description: Recombinant protein for human Protein phosphatase 1L

CMV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV100PA-KIT 1 Kit
EUR 1132

CMV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV105PA-KIT 1 Kit
EUR 1132

MSCV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV120PA-KIT 1 Kit
EUR 1132

MSCV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV125PA-KIT 1 Kit
EUR 1132

Multiplex gRNA Kit + EF1-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS700A-KIT 10 rxn
EUR 1132

Multiplex gRNA Kit + CAG-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS720A-KIT 10 rxn
EUR 1132

Multiplex gRNA Kit + CMV-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS740A-KIT 10 rxn
EUR 1132

T7 gRNA SmartNuclease Synthesis Kit (includes CAS510A-1 & T7 IVT synthesis reagents)

CAS510A-KIT 1 Kit
EUR 805

Cas9 Nickase: CMV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV200PA-KIT 1 Kit
EUR 1132

Cas9 Nickase: CMV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV205PA-KIT 1 Kit
EUR 1132

Cas9 Nickase: MSCV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV220PA-KIT 1 Kit
EUR 1132

Cas9 Nickase: MSCV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV225PA-KIT 1 Kit
EUR 1132

Genorise® Customized PCR primers for cloning and sequencing

GR108023 2 nmol
EUR 65

Multiplex gRNA Kit + Cas9 Nickase: EF1-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector

CAS750A-KIT 10 rxn
EUR 1132

Multiplex gRNA Kit + Cas9 Nickase: CAG-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector

CAS770A-KIT 10 rxn
EUR 1132

Multiplex gRNA Kit + Cas9 Nickase: CMV-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector

CAS790A-KIT 10 rxn
EUR 1132

Cas9 SmartNuclease Extra Ligation Kit [includes 5x ligation buffer (10 ul) and Fast ligase (2.5ul)]

CAS9LIG-KIT 1 Kit
EUR 153

Rat Retinoic Acid Early Transcript 1L ELISA kit

E02R0358-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Rat Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Retinoic Acid Early Transcript 1L ELISA kit

E02R0358-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Rat Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Retinoic Acid Early Transcript 1L ELISA kit

E02R0358-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rat Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Retinoic Acid Early Transcript 1L ELISA kit

E09R0358-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Monkey Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Retinoic Acid Early Transcript 1L ELISA kit

E09R0358-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Monkey Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Retinoic Acid Early Transcript 1L ELISA kit

E09R0358-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Monkey Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Retinoic Acid Early Transcript 1L ELISA kit

E08R0358-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Canine Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Retinoic Acid Early Transcript 1L ELISA kit

E08R0358-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Canine Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Retinoic Acid Early Transcript 1L ELISA kit

E08R0358-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Canine Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Retinoic Acid Early Transcript 1L ELISA kit

E01R0358-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Human Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Retinoic Acid Early Transcript 1L ELISA kit

E01R0358-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Human Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Retinoic Acid Early Transcript 1L ELISA kit

E01R0358-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Human Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Retinoic Acid Early Transcript 1L ELISA kit

E07R0358-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Porcine Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Retinoic Acid Early Transcript 1L ELISA kit

E07R0358-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Porcine Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Retinoic Acid Early Transcript 1L ELISA kit

E07R0358-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Porcine Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Retinoic Acid Early Transcript 1L ELISA kit

E04R0358-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Rabbit Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Retinoic Acid Early Transcript 1L ELISA kit

E04R0358-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Rabbit Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Retinoic Acid Early Transcript 1L ELISA kit

E04R0358-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rabbit Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Retinoic Acid Early Transcript 1L ELISA kit

E06R0358-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Goat Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Retinoic Acid Early Transcript 1L ELISA kit

E06R0358-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Goat Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Retinoic Acid Early Transcript 1L ELISA kit

E06R0358-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Goat Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Retinoic Acid Early Transcript 1L ELISA kit

E03R0358-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Mouse Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Retinoic Acid Early Transcript 1L ELISA kit

E03R0358-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Mouse Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Retinoic Acid Early Transcript 1L ELISA kit

E03R0358-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Mouse Retinoic Acid Early Transcript 1L in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

PinPoint-FC 293T Platform Kit for Targeted Gene Insertion (includes PIN320A-1, PIN200A-1, PIN510A-1 & PIN600A-1)

PIN320A-KIT 1 Kit
EUR 4941

PinPoint-FC Murine iPSC Platform Kit for Targeted Gene Insertion (includes PIN340iPS-1, PIN200A-1, PIN510A-1 & PIN600A-1)

PIN340iPS-KIT 1 Kit
EUR 4941

BCA Protein Assay Kit

AR0146-1L 1kit
EUR 456

Cytochrome P450 14a-demethylase inhibitor 1L

E1KS2146 2mg
EUR 365

Monoclonal SLINGSHOT-1L Antibody, Clone: 1A5C8

AMM07882G 0.1ml
EUR 528
Description: A Monoclonal antibody against Human SLINGSHOT-1L. The antibodies are raised in Mouse and are from clone 1A5C8. This antibody is applicable in WB and IHC, FC, ICC, E

Monoclonal SLINGSHOT-1L Antibody, Clone: 6C11G9

AMM07883G 0.1ml
EUR 528
Description: A Monoclonal antibody against Human SLINGSHOT-1L. The antibodies are raised in Mouse and are from clone 6C11G9. This antibody is applicable in WB and IHC, FC, ICC, E

1L TTE Glycerol Tolerant Buffer 20X

NAT1220 1L
EUR 134

1L Tris-Glycine Electroblotting Buffer 10X

NAT1240 1L
EUR 85

We also identified some of the genes responsible for the change in the score DGIE occur during cell differentiation is based on three single-cell dataset real. Our results show that single-cell analysis is based on inference network coupled with quantitative calculations can reveal key transcriptional regulators involved in cell differentiation and disease progression.

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