ATM mutations improve radio-sensitivity in wild-type isocitrate dehydrogenase-associated high-grade glioma: retrospective analysis using next-generation sequencing data
Background: To identify the relationship between somatic ataxia-telangiectasia mutated (ATM) mutation and improved radio-sensitivity, we retrospectively reviewed the next-generation sequencing data from patients diagnosed with glioma isocitrate dehydrogenase (IDH) -wildtype high quality.
Methods: We included 39 individuals (IDH) -wildtype high-grade glioma (diffuse astrocytoma n = 2, n = 10 anaplastic astrocytoma and glioblastoma n = 27) had no gross tumor resection and radiation therapy undergo the median total dose of 60 Gy in 30 fractions. ATM gene mutation status was obtained through generation sequencing using TruSight cancer panel 170. Tumor progression was defined by Response Assessment in Neuro-Oncology (Rano) criteria as well as neurological and clinical findings.
Results: Among the 39 samples, ATM mutations (mut ATM (+)) was detected in 26% of cases (n = 10).
No significant differences were observed in the patient or tumor characteristics. Among the 10 patients in the ATM mut (+), there are 6 patients with glioblastoma and four patients with anaplastic astrocytoma. Most mutations are missense mutations (n = 8, 80%). With a median follow-up of 16.5 mo (interquartile range, 11.4 to 19.8), ATM mut (+) exhibited one year of control in the field of 100% compared with 44.1% in ATM mut (-) group (p = 0.002). There was no difference in the rate of out-of-field control or overall survival between the two groups (p = 0.861 and p = 0.247, respectively).
Conclusions: Our results indicate that ATM mutations may be involved in the increase in radio-sensitivity with good control in the field despite the aggressive nature of IDH-wildtype high-grade glioma. Further studies are needed to uncover the potential role of ATM as a candidate biomarker and therapeutic target in high-grade glioma.
Whole-genome sequencing and Mycobacterium tuberculosis: Challenges in sample preparation and analysis of sequencing data
The number of patients with tuberculosis (TB) caused by resistant strains are still alarming. Therefore, it is necessary to determine the resilience of faster and more accurate, than with the currently used phenotypic and genotypic methods.
In recent years, technological advances have been made and the method of whole genome sequencing (WGS) has been introduced as part of routine clinical laboratory diagnostics. Comparing various mycobacterial genome variation with reference genome leads to a consistent evaluation of molecular epidemiology and resistance of Mycobacterium tuberculosis (M. tuberculosis) to a variety of anti-TB drugs.
The quality of sequencing data obtained is closely related to the type of samples and the methods used for DNA extraction and sequencing library preparation. In addition, the correct interpretation of the results is also affected by bioinformatics data processing. A large number of bioinformatics pipeline that is currently available, the sensitivity varies due to the different size of the database containing the relevant mutation. This review focuses on the individual steps in the workflow including sequencing and factors that may affect the interpretation of the final results.
comparative analysis suggests that miR-375 and miR-7 expression was substantially higher in the case of the control of non-Nen Nen. Correlation analysis showed that NENs from diverse anatomical sites have convergent program miRNA expression, may reflect the morphological and functional similarities.
TBE-Buffer 5X for DNA Sequencing |
|||
40121072-3 | Glycomatrix | 1 L | EUR 72.29 |
TBE-Buffer 5X for DNA Sequencing |
|||
40121072-4 | Glycomatrix | 4 L | EUR 192.14 |
DNA Library Prep Kit for IIlumina Sequencing |
|||
K1475-12 | Biovision | 12 Rxns | EUR 576 |
Genorise® Customized PCR primers for cloning and sequencing |
|||
GR108023 | Genorise Scientific | 2 nmol | EUR 65 |
Trypin for Mass & Sequencing |
|||
T9600-025 | GenDepot | 25ug | EUR 174 |
Trypin for Mass & Sequencing |
|||
T9600-100 | GenDepot | 100ug | EUR 262.8 |
Trypin for Mass & Sequencing |
|||
T9600-112 | GenDepot | 12x100ug | EUR 1988.4 |
Trypin for Mass & Sequencing |
|||
T9600-400 | GenDepot | 4x100ug | EUR 781.2 |
Chymotrypsin for Sequencing grade |
|||
C4001-010 | GenDepot | 4x25ug | EUR 375.6 |
Chymotrypsin for Sequencing grade |
|||
C4001-100 | GenDepot | 100ug | EUR 343.2 |
pOET Sequencing Primers |
|||
GWB-200100 | GenWay Biotech | 2 x 100 ul | Ask for price |
PCR DNA CLEAN-UP KIT |
|||
IB47035 | IBI Scientific | 2 X 96 WELL FORMAT KIT | EUR 305.5 |
PCR DNA CLEAN-UP KIT |
|||
IB47040 | IBI Scientific | 4 X 96 WELL FORMAT KIT | EUR 608.35 |
PCR DNA CLEAN-UP KIT |
|||
IB47050 | IBI Scientific | 10 X 96 WELL FORMAT KIT | EUR 1425.45 |
sequencing unit 33x45 cm |
|||
ESEQ1100-SYS | Consort | ea | EUR 1842 |
Sequencing Grade Chymotrypsin |
|||
RE013 | SAB | 100ug | EUR 309 |
sequencing system 20x50 cm |
|||
ESEQ1200-SYS | Consort | ea | EUR 1842 |
Sequencing Grade V8 Protease |
|||
RE014 | SAB | 50ug | EUR 209 |
SEPTA MAT, FOR 96 WELL PCR PLATES, SILICONE, GREY, NONSTERILE, FOR ABI MULTI-CAPILLARY SEQUENCING INSTRUMENTS, BULK |
|||
AM-96-SEPTA-3100 | CORNING | 10/pk | EUR 639.6 |
Description: Sealing Products; Sealing mats - Axygen |
Sequencing Grade Modified Trypsin |
|||
RE012 | SAB | 100ug | EUR 229 |
Sequencing Grade Carboxypeptidase B |
|||
RE011 | SAB | 100ug | EUR 99 |
ACES Sequencing Buffer 10X, pH 7.7 |
|||
21420000-1 | Glycomatrix | 1 L | EUR 138.62 |
ACES Sequencing Buffer 10X, pH 7.7 |
|||
21420000-2 | Glycomatrix | 4 L | EUR 456.17 |
SequaGel Sequencing System 1L Kit - 1KIT |
|||
NAT1136 | Scientific Laboratory Supplies | 1KIT | EUR 187.65 |
SequaGel Sequencing System 2.2L Kit - EACH |
|||
NAT1138 | Scientific Laboratory Supplies | EACH | EUR 318.6 |
Bovine Trypsin Purified Sequencing Grade |
|||
IBOTRYSEQ100UG | Innovative research | each | EUR 148 |
Description: Bovine Trypsin Purified Sequencing Grade |
Bovine Trypsin Purified Sequencing Grade |
|||
IBOTRYSEQ1MG | Innovative research | each | EUR 765 |
Description: Bovine Trypsin Purified Sequencing Grade |
Bovine Trypsin Purified Sequencing Grade |
|||
IBOTRYSEQ400UG | Innovative research | each | EUR 419 |
Description: Bovine Trypsin Purified Sequencing Grade |
EpiNext Bisulfite Sequencing Kit (Illumina) |
|||
P-1056 | EpiGentek |
|
|
Bovine Trypsin Purified Sequencing Grade Lyophilized |
|||
IBOTRYSEQLY100UG | Innovative research | each | EUR 130 |
Description: Bovine Trypsin Purified Sequencing Grade Lyophilized |
Bovine Trypsin Purified Sequencing Grade Lyophilized |
|||
IBOTRYSEQLY1MG | Innovative research | each | EUR 640 |
Description: Bovine Trypsin Purified Sequencing Grade Lyophilized |
Bovine Trypsin Purified Sequencing Grade Lyophilized |
|||
IBOTRYSEQLY400UG | Innovative research | each | EUR 344 |
Description: Bovine Trypsin Purified Sequencing Grade Lyophilized |
MagaDye™ 4 Color Sanger Sequencing Terminator Kit |
|||
17068 | AAT Bioquest | 5 nmoles | EUR 2091 |
PCR Clean-up Kit, |
|||
PC05 | GeneOn | 5 preps | Ask for price |
PCR Clean-up Kit, |
|||
PC100 | GeneOn | 100 preps | EUR 156 |
PCR Clean-up Kit, |
|||
PC200 | GeneOn | 200 preps | EUR 226.8 |
PCR Clean-up Kit, |
|||
PC50 | GeneOn | 50 preps | EUR 112.8 |
TuMinute PCR Clean-Up Kit |
|||
P-1005 | EpiGentek |
|
|
Bovine Alpha Chymotrypsin 3X Crystallized TLCK Treated Sequencing Grade |
|||
IBOCHYTLCKSG100UG | Innovative research | each | EUR 297 |
Description: Bovine Alpha Chymotrypsin 3X Crystallized TLCK Treated Sequencing Grade |
Bacteria-Derived Clostripain (Endoproteinase-Arg-C) Sequencing Grade Purified |
|||
IBCTCLOSGPF10UG | Innovative research | each | EUR 165 |
Description: Bacteria-Derived Clostripain (Endoproteinase-Arg-C) Sequencing Grade Purified |
Bacteria-Derived V8 Protease (Endoprotease Glu-C) Sequencing Grade Lyophilized |
|||
IBCTV8SEQLY250UG | Innovative research | each | EUR 784 |
Description: Bacteria-Derived V8 Protease (Endoprotease Glu-C) Sequencing Grade Lyophilized |
Bacteria-Derived V8 Protease (Endoprotease Glu-C) Sequencing Grade Lyophilized |
|||
IBCTV8SEQLY50UG | Innovative research | each | EUR 304 |
Description: Bacteria-Derived V8 Protease (Endoprotease Glu-C) Sequencing Grade Lyophilized |
PCR Clean-Up Mini Kit (50prep) |
|||
FAPCK-001 | Favorgen | 50 preps | EUR 144 |
PCR Clean-Up Mini Kit (200prep) |
|||
FAPCK-001-1 | Favorgen | 200 preps | EUR 202.8 |
PCR Clean-Up Mini Kit (300prep) |
|||
FAPCK-001-2 | Favorgen | 300 preps | EUR 226.8 |
PCR Clean-Up Mini Kit (50prep) |
|||
FAPCK_001 | Favorgen | 1 kit | EUR 16 |
PCR Clean-Up Mini Kit (200prep) |
|||
FAPCK_001-1 | Favorgen | 1 kit | EUR 54 |
PCR Clean-Up Mini Kit (300prep) |
|||
FAPCK_001-2 | Favorgen | 1 kit | EUR 69.5 |
PCR Clean-Up & Gel Extraction Kit |
|||
PDC01-0100 | Bio-Helix | 100 rxns | EUR 55 |
MicroElute PCR Clean Up Kit (50prep) |
|||
FAMPK-001 | Favorgen | 50 preps | EUR 151.2 |
MicroElute PCR Clean Up Kit (200prep) |
|||
FAMPK-001-1 | Favorgen | 200 preps | EUR 224.4 |
MicroElute PCR Clean Up Kit (100prep) (blister packing for columns) |
|||
FAMPK_001-1B | Favorgen | 1 kit | EUR 56 |
MicroElute PCR Clean Up Kit (50prep) (blister packing for columns) |
|||
FAMPK_001B | Favorgen | 1 kit | EUR 28 |
AxyPrep Mag PCR clean up -50mL - EACH |
|||
AXY1046 | Scientific Laboratory Supplies | EACH | EUR 1934.55 |
GF-1 PCR Clean-up Kit, 50 preps |
|||
GF-PC-050 | Vivantis | each | Ask for price |
GF-1 PCR Clean-up Kit, 100 preps |
|||
GF-PC-100 | Vivantis | each | Ask for price |
GF-1 PCR Clean-up Kit, 200 preps |
|||
GF-PC-200 | Vivantis | each | Ask for price |
96-well PCR Clean-Up Kit (1 prep) |
|||
FACKE-96001 | Favorgen | 1 prep | EUR 189.6 |
96-well PCR Clean-Up Kit (2 prep) |
|||
FACKE-96002 | Favorgen | 2 preps | EUR 255.6 |
96-well PCR Clean-Up Kit (4 prep) |
|||
FACKE-96004 | Favorgen | 4 preps | EUR 380.4 |
96-well PCR Clean-Up Kit (1 prep) |
|||
FACKE_96001 | Favorgen | 1 kit | EUR 45 |
96-well PCR Clean-Up Kit (2 prep) |
|||
FACKE_96002 | Favorgen | 1 kit | EUR 87.5 |
96-well PCR Clean-Up Kit (4 prep) |
|||
FACKE_96004 | Favorgen | 1 kit | EUR 168 |
AxyPrep Mag PCR clean up Kit-1mL - EACH |
|||
AXY1040 | Scientific Laboratory Supplies | EACH | EUR 102.6 |
AxyPrep Mag PCR clean up Kit-5mL - EACH |
|||
AXY1044 | Scientific Laboratory Supplies | EACH | EUR 410.4 |
Column-Pure Gel and PCR Clean-Up Kit |
|||
D516 | ABM | 100 Preparations | EUR 165 |
Eppendorf DNA LoBind tubes 0.5ml PCR clean - PK250 |
|||
E0030108035 | Scientific Laboratory Supplies | PK250 | EUR 35.1 |
Eppendorf DNA LoBind tubes 1.5ml PCR clean - PK250 |
|||
E0030108051 | Scientific Laboratory Supplies | PK250 | EUR 20.25 |
Eppendorf DNA LoBind tubes 2.0ml PCR clean - PK250 |
|||
E0030108078 | Scientific Laboratory Supplies | PK250 | EUR 22.95 |
FavorPrep Genomic DNA Clean-Up Kit (50prep) |
|||
FAGDC-001 | Favorgen | 50 preps | EUR 154.8 |
FavorPrep Genomic DNA Clean-Up Kit (200prep) |
|||
FAGDC-001-1 | Favorgen | 200 preps | EUR 244.8 |
FavorPrep Genomic DNA Clean-Up Kit (50prep) |
|||
FAGDC_001 | Favorgen | 1 kit | EUR 22.5 |
FavorPrep Genomic DNA Clean-Up Kit (200prep) |
|||
FAGDC_001-1 | Favorgen | 1 kit | EUR 81 |
AXYPREP MAG PCR CLEAN UP KIT- 5 ML - 110 PREPS |
|||
MAG-PCR-CL-5 | CORNING | 1/pk | EUR 175.2 |
Description: Bioscience Mag Beads; Magnetic PCR Clean Up |
AXYPREP MAG PCR CLEAN UP KIT- 50 ML - 1110 PREPS |
|||
MAG-PCR-CL-50 | CORNING | 1/pk | EUR 694.8 |
Description: Bioscience Mag Beads; Magnetic PCR Clean Up |
AXYPREP MAG PCR CLEAN UP KIT- 1 ML - (SAMPLE SIZE) |
|||
MAG-PCR-CL-1 | CORNING | 1/pk | EUR 69.6 |
Description: Bioscience Mag Beads; Magnetic PCR Clean Up |
96-well GE/PCR Clean Up Purification Kit (1 plates) |
|||
FAPKE-96001 | Favorgen | 1 prep | EUR 175.2 |
96-well GE/PCR Clean Up Purification Kit (2 plates) |
|||
FAPKE-96002 | Favorgen | 2 preps | EUR 225.6 |
96-well GE/PCR Clean Up Purification Kit (4 plates) |
|||
FAPKE-96004 | Favorgen | 4 preps | EUR 328.8 |
96-well GE/PCR Clean Up Purification Kit (1 plates) |
|||
FAPKE_96001 | Favorgen | 1 kit | EUR 36 |
96-well GE/PCR Clean Up Purification Kit (2 plates) |
|||
FAPKE_96002 | Favorgen | 1 kit | EUR 68.5 |
96-well GE/PCR Clean Up Purification Kit (4 plates) |
|||
FAPKE_96004 | Favorgen | 1 kit | EUR 134.5 |
Eppendorf tubes 5mL screw cap DNA LoBind PCR clean - PK200 |
|||
E0030122348 | Scientific Laboratory Supplies | PK200 | EUR 86.4 |
PAGE Clean Up Kit |
|||
06441-50 | NACALAI TESQUE | 1KIT | EUR 269.5 |
GF-1 96-well PCR Clean-up Kit, 96 x 5 plates |
|||
GF-96-C05 | Vivantis | each | Ask for price |
GF-1 96-well PCR Clean-up Kit, 96 x 10 plates |
|||
GF-96-C10 | Vivantis | each | Ask for price |
VAHTS DNA Clean Beads |
|||
N411-01 | Vazyme | 5 ml | EUR 72.5 |
VAHTS DNA Clean Beads |
|||
N411-02 | Vazyme | 60 ml | EUR 475 |
VAHTS DNA Clean Beads |
|||
N411-03 | Vazyme | 450 ml | EUR 1892.5 |
Tubes 5mL screw cap PCR clean - PK200 |
|||
E0030122313 | Scientific Laboratory Supplies | PK200 | EUR 78.3 |
Micro test tubes 3810X PCR clean - PK1000 |
|||
E0030125215 | Scientific Laboratory Supplies | PK1000 | EUR 55.35 |
Protein Assay CBB Clean Up Kit |
|||
11611-60 | NACALAI TESQUE | 1KIT | EUR 67.9 |
epT.I.P.S. Reload 384 IVD PCR clean 0.5 - 100uL 53mm |
|||
E0030076079 | Scientific Laboratory Supplies | PK3840 | EUR 539.22 |
Zenoquick DNA Clean & Concentrator-5 |
|||
Z2001-050 | GenDepot | 50 prpe | EUR 216 |
epT.I.P.S. G Reload 384 PCR clean 0.5 - 100uL 52.8mm - PK3840 |
|||
E0030076010 | Scientific Laboratory Supplies | PK3840 | EUR 669.6 |
ep LoRetention PCR clean 2-200ul 10 x 96 reloads |
|||
E0030072022 | Scientific Laboratory Supplies | PK960 | EUR 80.94 |
ep LoRetention PCR clean 50-1000ul 10 x 96 reloads |
|||
E0030072030 | Scientific Laboratory Supplies | PK960 | EUR 80.94 |
Genorise® Gel DNA Purification Mini Kit-PCR Clean Kit- 50 |
|||
GR101080 | Genorise Scientific | 50 | EUR 148 |
Genorise® Gel DNA Purification Mini Kit-PCR Clean Kit- 100 |
|||
GR101080-100 | Genorise Scientific | 100 | EUR 267 |
Genorise® Gel DNA Purification Mini Kit-PCR Clean Kit- 200 |
|||
GR101081 | Genorise Scientific | 200 | EUR 477 |
Genorise® Gel DNA Purification Mini Kit-PCR Clean Kit- 500 |
|||
GR101081-500 | Genorise Scientific | 500 | EUR 1074 |
ep LoRetention PCR clean 0.1-10ul 10 x 96 reloads |
|||
E0030072006 | Scientific Laboratory Supplies | PK960 | EUR 88.92 |
ep LoRetention PCR clean 0.5-20ul 10 x 96 reloads |
|||
E0030072014 | Scientific Laboratory Supplies | PK960 | EUR 85.5 |
epT.I.P.S. Reload 384 IVD PCR clean 0.1 - 20uL 42mm |
|||
E0030076060 | Scientific Laboratory Supplies | PK3840 | EUR 539.22 |
Eppendorf Protein LoBind tubes 0.5ml PCR clean - PK100 |
|||
E0030108094 | Scientific Laboratory Supplies | PK100 | EUR 18.9 |
Eppendorf Protein LoBind tubes 1.5ml PCR clean - PK100 |
|||
E0030108116 | Scientific Laboratory Supplies | PK100 | EUR 14.85 |
Eppendorf Protein LoBind tubes 2.0ml PCR clean - PK100 |
|||
E0030108132 | Scientific Laboratory Supplies | PK100 | EUR 22.95 |
EpiQuik DNA Clean and Concentrator Kit |
|||
P-1068 | EpiGentek | 50 Preparations | EUR 158 |
epT.I.P.S. G Reloads 384 PCR clean 0.1 - 20uL 42mm - PK3840 |
|||
E0030076001 | Scientific Laboratory Supplies | PK3840 | EUR 669.6 |
Gel Permeation Clean Up Calibration Standard - 5ML |
|||
GPC-CAL-91 | Scientific Laboratory Supplies | 5ML | EUR 116.1 |
Tips PCR Clean 50uL 103 mm dark green 10x96 - EACH |
|||
E0030073649 | Scientific Laboratory Supplies | EACH | EUR 113.4 |
Combitips Adv. PCR Clean 1.0ml 4 packs of 25 - PK100 |
|||
E0030089790 | Scientific Laboratory Supplies | PK100 | EUR 156.6 |
Combitips Adv. PCR Clean 2.5ml 4 packs of 25 - PK100 |
|||
E0030089804 | Scientific Laboratory Supplies | PK100 | EUR 156.6 |
Combitips Adv. PCR Clean 10ml 4 packs of 25 - PK100 |
|||
E0030089820 | Scientific Laboratory Supplies | PK100 | EUR 156.6 |
Combitips Adv. PCR Clean 25ml 4 packs of 25 - PK100 |
|||
E0030089839 | Scientific Laboratory Supplies | PK100 | EUR 183.6 |
Combitips Adv. PCR Clean 50ml 4 packs of 25 - PK100 |
|||
E0030089847 | Scientific Laboratory Supplies | PK100 | EUR 197.1 |
Eppendorf Conical Tubes 25mL with snap cap PCR clean - PK200 |
|||
E0030118413 | Scientific Laboratory Supplies | PK200 | EUR 79.11 |
Eppendorf Safe-Lock micro test tubes 0.5ml PCR clean - PK500 |
|||
E0030123301 | Scientific Laboratory Supplies | PK500 | EUR 64.8 |
Eppendorf Conical Tubes 25mL with screw cap PCR clean - PK200 |
|||
E0030122429 | Scientific Laboratory Supplies | PK200 | EUR 87.75 |
Eppendorf Safe-Lock micro test tubes 1.5ml PCR clean - PK1000 |
|||
E0030123328 | Scientific Laboratory Supplies | PK1000 | EUR 64.8 |
Eppendorf Safe-Lock micro test tubes 2.0ml PCR clean - PK1000 |
|||
E0030123344 | Scientific Laboratory Supplies | PK1000 | EUR 87.75 |
Eppendorf tubes 5mL screw cap protein LoBind PCR clean - PK200 |
|||
E0030122356 | Scientific Laboratory Supplies | PK200 | EUR 117.45 |
Eppendorf Tubes 5.0ml PCR clean 200 pcs. 2 bags of 100 tubes each - EACH |
|||
E0030119460 | Scientific Laboratory Supplies | EACH | EUR 57.38 |
Eppendorf Conical Tubes 25mL with snap cap Starter Pack PCR clean - EACH |
|||
E0030118502 | Scientific Laboratory Supplies | EACH | EUR 135 |
Eppendorf Conical Tubes 25mL with screw cap Starter Pack PCR clean - EACH |
|||
E0030122500 | Scientific Laboratory Supplies | EACH | EUR 139.05 |
Automatic FillDrain for Clean Steam for Rodwell autoclaves - EACH |
|||
AUT1351 | Scientific Laboratory Supplies | EACH | EUR 2619 |
Eppendorf Protein LoBind Tubes 5.0ml PCR clean 100 pcs. 2 bags of 50 tubes each - EACH |
|||
E0030108302 | Scientific Laboratory Supplies | EACH | EUR 56.7 |
Electrode Clean Sol Pepsin/HCl for Removal of Proteins - 1L |
|||
ECSF | Scientific Laboratory Supplies | 1L | EUR 214.44 |
Electrode Clean Sol Pepsin/HCl for Removal of Proteins - 250ML |
|||
ECS-250ML | Scientific Laboratory Supplies | 250ML | EUR 40.5 |
Electrode Clean Sol Pepsin/HCl for Removal of Proteins - 100ML |
|||
ECS1 | Scientific Laboratory Supplies | 100ML | EUR 157.16 |
VAHTS RNA Clean Beads |
|||
N412-01 | Vazyme | 5 ml | EUR 87.5 |
VAHTS RNA Clean Beads |
|||
N412-02 | Vazyme | 40 ml | EUR 340 |
VAHTS RNA Clean Beads |
|||
N412-03 | Vazyme | 450 ml | EUR 2475 |
gelcaster for sequencer |
|||
ESEQ1000-CAST | Consort | ea | EUR 524.4 |
Lancer Clean Detergent - 10L |
|||
CLE1136 | Scientific Laboratory Supplies | 10L | EUR 94.5 |
RNA Clean and Concentrator Kit |
|||
K1069-20 | ApexBio | 20 preps | EUR 88 |
Description: Efficient RNA purification kit |
Electrode Clean Sol Organic - 5L |
|||
OECS5 | Scientific Laboratory Supplies | 5L | EUR 1101.6 |
T-Pro Aqua EZ Clean (M) |
|||
JT90-R001M | T-Pro Biotechnology | 500ml/BT | EUR 398.4 |
T-Pro Aqua EZ Clean (S) |
|||
JT90-R001S | T-Pro Biotechnology | 100ml/BT | EUR 181.2 |
20 bp random library with flanking sequence; DNA aptamer |
|||
DAL-N-20 | Alpha Diagnostics | 100 ug | EUR 343.2 |
30 bp random library with flanking sequence; DNA aptamer |
|||
DAL-N-30 | Alpha Diagnostics | 100 ug | EUR 416.4 |
40 bp random library with flanking sequence; DNA aptamer |
|||
DAL-N-40 | Alpha Diagnostics | 100 ug | EUR 489.6 |
PCR magnetic Cleanup |
|||
TBS6029-200 | Tribioscience | 200 Tests | EUR 189 |
Mouse GC- rich sequence DNA- binding factor, Tcf9 ELISA KIT |
|||
ELI-12525m | Lifescience Market | 96 Tests | EUR 1038 |
Human GC- rich sequence DNA- binding factor, TCF9 ELISA KIT |
|||
ELI-27490h | Lifescience Market | 96 Tests | EUR 988.8 |
Bolle COVERALL CLEAN Cleanroom Safety Goggles - EACH |
|||
SAF1954 | Scientific Laboratory Supplies | EACH | EUR 26.19 |
GC-Rich Sequence DNA-Binding Factor 1 (GCFC1) Antibody |
|||
20-abx217653 | Abbexa |
|
|
GC-Rich Sequence DNA-Binding Factor 1 (GCFC1) Antibody |
|||
abx217653-100tests | Abbexa | 100 tests | Ask for price |
GC-Rich Sequence DNA-Binding Factor 1 (GCFC1) Antibody |
|||
abx217653-200tests | Abbexa | 200 tests | Ask for price |
GC-Rich Sequence DNA-Binding Factor 1 (GCFC1) Antibody |
|||
abx217653-20tests | Abbexa | 20 tests | EUR 87.5 |
GC-Rich Sequence DNA-Binding Factor 1 (GCFC1) Antibody |
|||
abx375543-96tests | Abbexa | 96 tests | EUR 337.5 |
Adhesive PCR Plate Clear Films for PCR Applications |
|||
GP502 | GenDepot | 100 sheets | EUR 306 |
Mouse GC- rich sequence DNA- binding factor 1, Gcfc1 ELISA KIT |
|||
ELI-37633m | Lifescience Market | 96 Tests | EUR 1038 |
Human GC- rich sequence DNA- binding factor 1, GCFC1 ELISA KIT |
|||
ELI-08155h | Lifescience Market | 96 Tests | EUR 988.8 |
GenepHlow™ PCR Cleanup Kit |
|||
DFC004 | Geneaid Biotech | each | EUR 3 |
GenepHlow™ PCR Cleanup Kit |
|||
DFC100 | Geneaid Biotech | each | EUR 36.3 |
GenepHlow™ PCR Cleanup Kit |
|||
DFC300 | Geneaid Biotech | each | EUR 98 |
West-Q Femto Clean ECL Solution |
|||
W3680-010 | GenDepot | 100ml | EUR 403.2 |
Using machine learning approach, we identified 17 miRNAs to distinguish 15 Nen type of pathological and then build a classifier multilayer, correctly identified 217 (98%) of the 221 samples and overturning a histological diagnosis.